1849 Charity Opheral is granted a preacher's license by the United Brethren Church.1851 Lydia Sexton is recommended as a "pulpit speaker" by the United Brethren General Conference.
1856 Clementina Rowe Butler and her husband William arrive as the first Methodist Episcopal Church missionaries to India.
In 1872, they establish a Methodist Episcopal mission in Mexico.
1878 Lochie Rankin goes to China as the first missionary of the Methodist Episcopal Church.
1880 Anna Howard Shaw and Anna Oliver are refused ordination rights by the Methodist Episcopal General Conference.
1922 Evangelical Church is formed, reuniting the Evangelical Association and a splinter group, the United Evangelical Church.
1939 The Methodist Church is formed through the union of the Methodist Episcopal Church, the Methodist Episcopal Church, South and the Methodist Protestant Church.
1888 Five women, including Frances Willard who is the president of the Women's Christian Temperance Union, are elected lay delegates to the Methodist Episcopal General Conference. The denomination establishes a deaconess program for laywomen.
Deaconesses serve the church in any capacity not requiring full clergy rights in ministries of love, justice and service.
Isabella Thoburn and Clara Swain leave for India where Thoburn launches a college in Lucknow that bears her name. Swain begins medical work in Bareli, and a hospital is later named in her honor.
1873 Anna Howard Shaw acquires a local preacher's license in the Methodist Episcopal Church.
1835 Phoebe Palmer, evangelist and mother of the American holiness movement, conducts weekly prayer meetings in her home.